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Article in Journal of Biological Physics and Chemistry-March 2017

 

Usage of the herbicide glyphosate on core crops in the USA has increased exponentially over the past two decades, in step with the exponential increase in autoimmune diseases including autism, multiple sclerosis, inflammatory bowel disease, type 1 diabetes, coeliac disease, neuromyelitis optica and many others. In this paper we explain how glyphosate, acting as a non-coding amino acid analogue of glycine, could erroneously be integrated with or incorporated into protein synthesis in place of glycine, producing a defective product that resists proteolysis.

Glyphosate pathways to modern diseases VI:Prions, amyloidoses and autoimmunE neurological diseases

Journal of International Medical Research-January 20, 2017

The wide range of factors associated with the induction of autism is invariably linked with either inflammation or oxidative stress, and sometimes both. The use of acetaminophen in babies and young children may be much more strongly associated with autism than its use during pregnancy, perhaps because of well-known deficiencies in the metabolic breakdown of pharmaceuticals during early development. Thus, one explanation for the increased prevalence of autism is that increased exposure to acetaminophen, exacerbated by inflammation and oxidative stress, is neurotoxic in babies and small children. This view mandates extreme urgency in probing the long-term effects of acetaminophen use in babies and the possibility that many cases of infantile autism may actually be induced by acetaminophen exposure shortly after birth. 

The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism

By Richard Gale and Dr. Gary Null

Global Research, September 16, 2015

Progressive Radio Network 15 

The year 2015 hasn’t been kind to Monsanto. In March, the World Health Organization declared that the company’s flagship product, its herbicide glyphosate or Roundup, is a probable human carcinogen. Increasingly, national health ministries are taking a hard second look at glyphosate’s health and environmental dangers and efforts are underway to ban the herbicide.[1] To protect its citizens, last year the Netherlands, Bermuda and Sri Lanka have either banned or imposed strict limits on Roundup. Last June, France banned its use in gardens. Brazil, Germany and Argentina are considering legislative bans. And this month, California’s environmental protection agency launched plans to label Roundup as a carcinogen.[2]

Monsanto’s Sealed Documents Reveal the Truth behind Roundup’s Toxicological Dangers

Background:

The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear.

Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study
Randomized controlled trial of vitamin D supplementation in children with autism spectrum disorder.

Abstract

BACKGROUND:

Autism spectrum disorder (ASD) is a frequent developmental disorder characterized by pervasive deficits in social interaction, impairment in verbal and nonverbal communication, and stereotyped patterns of interests and activities. It has been previously reported that there is vitamin D deficiency in autistic children; however, there is a lack of randomized controlled trials of vitamin D supplementation in ASD children.

Treatment of the Fluoroquinolone Associated Disability
the pathobiochemical implications

 

Abstract

Long term Fluoroquinolone Associated Disability (FQAD) after fluoroquinolone (FQ) antibiotic therapy appears in recent years a significant medical and social problem, because patients suffer for many years after prescribed antimicrobial FQ-treatment from tiredness, concentration problems, neuropathies, tendinopathies and other symptoms. The knowledge about the molecular activity of FQs in the cells remains unclear in many details. The effective treatment of this chronic state remains difficult and not effective. The current paper reviews the pathobiochemical properties of FQs, hints the directions for further research and reviews the research concerning the proposed treatment of patients. 

“The joy of discovery is certainly the liveliest that the mind of man can ever feel” —Claude Bernard

Cold and Flu Season- prevention strategies

It is October and school is in full swing. If you do “catch” a virus of any kind, try and have a “Sick Kit” already on standby to start right away. I personally can not afford to get sick because it usually ends up in a sinusitis with an overall illness length of two months. When I “hit” the illness within hours of onset with high doses of the Sick Kit components, I am generally over it within 12-36 hrs. Certainly not a guarantee, but there is NO down side to this approach. As an adult, I boost my Vit 3 to 50,000 u daily for four or five days, get on Liposomal Vit C 3-4 grams three times daily for a few days, take around 30 mg zinc (the 7 mg zinc/elderberry lozenges), and some sort of immune booster like echinacea or turkeytail mushroom extract.

I want to re-address this fever control issue yet again. I know that a parent's first instinct when their child has a fever is to get rid of it as quickly as possible; to make things better. Remember that fever has a beneficial function during illness. It enhances immune function and allows the child to get over the infection more expeditiously. When we drop that fever, the immune system may founder. In the process of trying to "make things better", sometimes we impede the very process that will facilitate that. The use of acetaminophen has taken a growing center stage in some medical circles as we wrestle with the realities of a logarithmic growth in autism. What on earth do the two have to do with each other? In this review article emanating from the reputable halls of Harvard University School of Medicine and Duke University,

Acetaminophen–Please hold off on using for now

Through our genetic testing as we find more and more kids who are at risk for peroxinitrite oxidative damage, we are looking for safe ways to mitigate this. This Italian study findsVit C and oils from Bay leaves and Coriander to score highly. Currently, for these at risk kids, we are using maintenance dose of liposomal Vit C 500-1000mg daily. —Dr. Brus

 

Essential oils of commonly used plants as inhibitors of peroxynitrite-induced tyrosine nitration

By Silvio Chericoni, Jose` M. Prieto, Patrizia Iacopini, Ivano Morelli

Abstract

The essential oils obtained from fifteen relevant and commonly used plants belonging to Cruciferae, Lamiaceae, Lauraceae, Apiaceae, and Zingiberaceae were screened using an in vitro model of peroxynitrite-induced tyrosine nitration.  

peroxynitrite-inhibition by essential oils

I think of some of the things we have recommended in Pediatrics out of convenience, tradition, lack of adequate thoughtfulness, or, worse, out of downright ignorance and I cringe. In January of this year the American College of Obstetricians and Gynecologists (ACOG) released a committee opinion that was meant to guide practice in the specific area of timing of cord clamping after a baby is born. It seems that the midwives had it right all along; delaying clamping of that cord may have benefits that reach from the immediate setting of mitigating birth trauma all the way to the possible enhancement of the aging brain. 

Delayed Cord Clamping–Midwives Win the Argument
Other Articles of Interest

Glyphosate pathways to modern diseases V: Amino acid analogue of glycine in diverse 

Proposed No Significant Risk Level for the chemical glyphosate to be adopted into regulation https://goo.gl/BYavDm

Glyphosate, pathways to modern diseases IV:

cancer and related pathologies 

https://goo.gl/MKCKBC

Cerebellar level of neurotransmitters in rats exposed to paracetamol (acetaminophen) during development 

One of the challenges of transforming your family's dietary intake from the SAD to the Real Food diet is getting enough information under your belt on not only the kinds of foods to purchase but how to fix them. I want to share some of the material from the Institute of Functional Medicine conferences that may be helpful that way. We talk a lot about "eating the rainbow" and the importance of getting those powerful colorful antioxidants and polyphenolic compounds into your child's body. Herein lies the real future of medicine!

Eating "The Rainbow"